Hardest CHEM classes at UMich

Ranked by average GPA from official grade distributions. Only courses with at least 100 graded students.

1. CHEM 215: Struct&react II Average GPA 2.88, 4,108 students
2. CHEM 210: Struct & React I Average GPA 2.90, 5,015 students
3. CHEM 351: Biochem Fundamentals Average GPA 3.14, 548 students
4. CHEM 302: Inorg Chem Average GPA 3.21, 157 students
5. CHEM 241: Intro to Chem Analy Average GPA 3.27, 258 students
6. CHEM 230: P Chem Princ&appl Average GPA 3.42, 1,863 students
7. CHEM 451: Adv Biochem I Average GPA 3.48, 255 students
8. CHEM 130: G Chem Invst&R Prin Average GPA 3.49, 6,275 students
9. CHEM 245: Biomed Chem Average GPA 3.54, 193 students
10. CHEM 420: Int Org Chem Average GPA 3.57, 167 students
11. CHEM 262: Math Met Phys Sci Average GPA 3.58, 247 students
12. CHEM 515: Organometallic Chem Average GPA 3.60, 128 students
13. CHEM 260: Chem Principles Average GPA 3.66, 735 students
14. CHEM 453: Biophys Chem I Average GPA 3.67, 223 students
15. CHEM 211: Invest Chem Average GPA 3.68, 5,534 students
16. CHEM 421: Org Chem Drug Des Average GPA 3.70, 130 students
17. CHEM 216: Syn Char Org Average GPA 3.71, 4,192 students
18. CHEM 105: Changing Atmos Average GPA 3.74, 335 students
19. CHEM 352: Intro Biochem Lab Average GPA 3.78, 370 students
20. CHEM 126: Gen Chem Lab II Average GPA 3.86, 7,608 students
21. CHEM 125: Gen Chem Lab I Average GPA 3.87, 9,086 students
22. CHEM 452: Adv Biochem II Average GPA 3.87, 264 students
23. CHEM 597: Intro to Grad Res Average GPA 3.98, 361 students
24. CHEM 220: Teach Exp Undergr Average GPA 3.99, 373 students
25. CHEM 398: Ug Res Biochem Average GPA 3.99, 263 students
26. CHEM 516: Prof Dev Chem Average GPA 3.99, 226 students
27. CHEM 415: Res Con in Chem Res Average GPA 4.00, 139 students

See also: Easiest classes, UMich course catalog, CHEM course catalog.